Potential Treatment for Rett Syndrome Through Maintenance of X-inactivation
Aging, Environment, & DiseaseChromatin StructureDNA Methylation and Hydroxymethylation

Maintenance of X-inactivation: A Step Towards a Potential Treatment for Rett Syndrome

Not only do the brown and black splotches of fur on calico cats make them pretty cute, they also reflect a moment early in mammalian development called X-chromosome inactivation. While females have two X-chromosomes, males only have one, so to ensure that the expression of genes on the X-chromosome is …