shutterstock_57261607 (1)
Aging, Environment, & DiseaseDNA Methylation and HydroxymethylationHistone Modifications

Epigenetic Basis of Substance Abuse

Substance abuse disorders are psychiatric disorders illnesses that impact patients severely in several biopsychosocial spheres. The criteria for the diagnosis of amphetamine and methamphetamine use disorders  include compulsive abuse of these substances despite adverse medicolegal consequences. Research on the basic neurobiology of these human disorders has focused on the use …

shutterstock_232134673 (1)
Aging, Environment, & DiseaseDevelopmental Biology & Stem CellsUncategorized

Early-life Exposure to Substance Abuse and the Risk for Type 2 Diabetes

Type 2 diabetes (T2D) is a chronic non-communicable disease that generally develops after the age of 40 and therefore believed to be associated with aging. There is, however,increasing experimental and epidemiological evidence that risk of T2D and obesity which is an important risk factor for T2D may be epigenetically programmed during critical windows …