Losing Heterochromatin to Determine Cell Fate
Chromatin StructureDevelopmental Biology & Stem Cells

Losing Heterochromatin to Determine Cell Fate

In the moments after fertilization, the tiny mass that is the embryo sets in motion developmental programs that will transform it into a human being. One of the earliest steps in human development is the formation of the germ layers. Humans and other animals in the Chordata phylum, have three …

READ MORE →
Simultaneous Gene Expression and Chromatin Landscape in Single Cells
Tools & Technology

A Simultaneous Picture of Gene Expression and Chromatin Landscape in Single Cells

As we move through the day, it’s easy to forget that individual cells, organized into tissues and tissues into organs, act in harmony to give us life. Over the years, scientists have developed new techniques to investigate how gene expression, chromatin state, and methylation determines developmental behavior, at the level …

READ MORE →