Sex Influences Brain Aging by Impacting DNA Methylation
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Sex Influences Brain Aging by Impacting DNA Methylation

While sex differences across aging and in the incidence of neurodegenerative diseases are well documented, relatively little data is available that compares sex-specific epigentic changes in the aging brain.1  Recent studies have identified specific loci with age-realted hyper- or hypo- methylation changes in liver, lung, and heart – but no …

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Sex Differences in the zebrafish brain.
Developmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

Plenty of Fish in the Sea but Only Two Kinds of Brains: Epigenetic Sex differences in Zebrafish Brain

Phenotypic differences between males and females of a species are referred to as sexual dimorphism. Sexual dimorphism manifests not only in morphological traits, but also in physiological and behavioural traits. In organisms that do not have sex chromosomes, males and females are both derived from a nearly identical genome. Such …

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Developmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

Battle of the Sexes: Autosomal DNA methylation tells us that men and women are more different than we thought

The genetic factors that give rise to the obvious morphological differences between males and females have long been known. Recently however, some less obvious disparities have emerged at the molecular level in the form of sex specific metabolic profiles, where any attempts to attribute these differences to genomic variations in …

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