Epigenetics and Obesity
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Epigenetic Marks Associated to Severe Obesity

There is growing evidence that DNA methylation might contribute to obesity. Candidate gene methylation studies in animal models and humans have demonstrated methylation changes in promoters of various genes that are implicated in obesity, appetite control and/or metabolism, insulin signaling, immunity, growth and circadian clock regulation. Severe obesity in children …

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Aging, Environment, & DiseaseTools & Technology

Can Epigenetics Help Cure Diabetes and Obesity?

Sunitha Meruvu1, John Bowman2, Mahua Choudhury1 1Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, TX, USA 2 Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, TX, USA Obesity poses a serious burden on society, …

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Aging, Environment, & DiseaseDNA Methylation and HydroxymethylationImprinting and Inheritance

Listen Up Dads! Paternal Weight and Obesity Influences Sperm Epigenetics

The obesity epidemic is a widely discussed, but controversial topic. Although diet and exercise are the best way to combat weight gain, some people seem to gain weight easier than others and have a more difficult time getting rid of it. The role of maternal and prenatal nutrition is concretely …

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Aging, Environment, & DiseaseDevelopmental Biology & Stem CellsUncategorized

Early-life Exposure to Substance Abuse and the Risk for Type 2 Diabetes

Type 2 diabetes (T2D) is a chronic non-communicable disease that generally develops after the age of 40 and therefore believed to be associated with aging. There is, however,increasing experimental and epidemiological evidence that risk of T2D and obesity which is an important risk factor for T2D may be epigenetically programmed during critical windows …

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Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Obesogens: The epigenetic interaction between nature and nurture on risk of obesity

More than 35% of the U.S. population is considered clinically obese (body mass index of > 30), while 68% of the U.S. is considered overweight (body mass index of > 25) 1. Obesity is known to have adverse health effects, impacting the risk and prognosis for a number of diseases, …

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