A Flash-Frozen View of Condensing Chromatin
Chromatin Structure

A Flash-Frozen View of Condensing Chromatin

For cells to divide, they must first condense their DNA into the X-shape familiar from introductory biology textbooks. While the process of cell division has been studied for over 100 years, how exactly our DNA condenses in three-dimensions within the nucleus remains a mystery. To better understand this condensation process, …

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Aging, Environment, & DiseaseChromatin StructureHistone Modifications

Gene Transcription: Not Always Dictated by Histone Modifications!

The proper regulation of gene expression is of fundamental importance in the maintenance of normal growth and development.  Misregulation of genes can lead to such outcomes as cancer, diabetes and neurodegenerative disease.  A key step in gene regulation occurs during the transcription of the chromosomal DNA into messenger RNA by …

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