Epigenetic Link to Recurrent Miscarriage
Aging, Environment, & DiseaseChromatin StructureDevelopmental Biology & Stem Cells

An Epigenetic Link to Recurrent Miscarriage

Miscarriage, or natural loss of a pregnancy, is a common reproductive problem and can be upsetting for families trying to have a child. Recurrent miscarriage (RM) – two or more miscarriages – often occur because of problems that arise very early in embryonic development. A common cause of RM is …

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Hypomethylation and Genetic Instability in Monosomy Blastocysts May Contribute to Decreased Implantation Potential
Developmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

Epigenetics of Early Pregnancy Loss: Hypomethylation and Genetic Instability May Contribute to Decreased Implantation Potential of Monosomy Blastocysts

Blair R. McCallie1,3, Jason C. Parks1,3, Alyssa L. Patton1, Darren K. Griffin3, William B. Schoolcraft2, Mandy G. Katz-Jaffe1,2 1 National Foundation for Fertility Research, Lone Tree, Colorado, 80124, United States of America, 2 Colorado Center for Reproductive Medicine, Lone Tree, Colorado, 80124, United States of America, 3 School of Biosciences, …

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