How Jet Lag Impacts Epigenetics
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Up All Night and Asleep All Day: How Jet Lag Impacts Epigenetics

Anyone who has ever dragged themselves off of a red-eye flight, understands the exhaustion of jet lag. Depending on how far you’ve traveled, the effects of jet lag can last from days to weeks, leading to sleepless nights and tired days as your body attempts to reset its circadian clock. …

Gene Transcription
Regulatory RNA

A new role for miRNAs: Transcriptional Gene Activation by Nuclear Activating miRNA (namiRNAs)

MiRNAs are small non-coding RNAs that carry diverse epigenetic and post-transcriptional mechanisms. Primarily, they have been studied for their function as a negative gene expression regulator, leaving their roles in activating gene expression poorly understood. Xiao et al.reports that miRNAs in the nucleus mediate gene activation by interacting with enhancer elements …