When the writing is wrong: PRMT5 histone methylation promotes invasivity and metastasis in a range of human cancers
Aging, Environment, & DiseaseHistone Modifications

When the writing is wrong: PRMT5 histone arginine methylation promotes invasivity and metastasis in a range of human cancers

Cancer metastasis occurs when cancer cells leave a primary tumor and invade other tissues. Generally, this leads to a poor prognosis for patients. Underlying epigenetic mechanisms of tumor progression are poorly understood but are of great interest for developing new approaches of treatment in the clinic. Cancer etiology is highly …

READ MORE →
shutterstock_320367446
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Identification of 21 DNA Hypermethylated Hotspots Associated with Breast Cancer Metastasis

Breast cancer is one of the most common diseases in women and almost an eighth of the women population is suffering from breast cancer. Currently, there are several methods to diagnose and treat breast cancer, including genetic screening. In 2013, Angelina Jolie announced that she carried the BRCA1 mutation and …

READ MORE →