sperm epigenetics
Developmental Biology & Stem CellsDNA Methylation and HydroxymethylationHistone ModificationsRegulatory RNA

Don’t forget all that dad has done for you.. and your epigenome.. this father’s day!

In mammals, the recognition and fusion between the sperm from the father and the oocyte from the mother gives rise to offspring. Therefore, the production of functional, flagella-containing motile sperm is the prerequisite for successful fertilization in nature. In human females, there is typically only one oocyte ovulated during each …

Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Hope for the Future: MTHFR as a Novel Biomarker for Infertility

The field of epigenetics plays a key role in multiple developmental diseases and processes. When dealing with infertility issues, DNA methylation should be looked at as a potential factor. Approximately 1% of infertile couples experience Recurrent Spontaneous Abortion (RSA), defined as the miscarriage of two or more pregnancies before 20 …