Histones in Paternal Epigenetic Inheritance
Histone ModificationsImprinting and Inheritance

A Role for Histones in Paternal Epigenetic Inheritance

A group of children grew up in the same neighborhoods of Quebec in the late 1960’s, but only some of them would reach their fifth birthday. In one of the first studies of its kind, Fabia and Thuy combed through hospital records to ask what made these children different from …

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Chaperoning Histone Inheritance
Chromatin StructureImprinting and Inheritance

Chaperoning Histone Inheritance

One of the great mysteries of epigenetics is how histones, the eponymous beads on a DNA string, are divided onto newly synthesized DNA strands during cell division. Histones carry modifications that serve as important signals in determining gene expression, regulating developmental programs, and their alteration can even mark disease states …

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