Altering Heterochromatin Disguises Malaria from Host
Chromatin StructureHistone Modifications

Hidden in Plain Sight: How Altering Heterochromatin Disguises Malaria from its Host

Like a criminal adopting a disguise to evade detection, malaria parasites inside red blood cells express specific proteins on the blood cell surface to hide from the immune system. When the malaria parasites, Plasmodium falciparum, are eventually detected, they simply switch the identity of the surface protein in a process …

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Mapping the Chromatin Landscape of Cancers
Aging, Environment, & DiseaseChromatin StructureTools & Technology

Mapping the Chromatin Landscape of Cancers

A betrayal of our own cells against us, cancer is a devastating disease that affects over 18 million people world-wide [1]. With more than 200 different types of cancer, most with diverse modes of action and variable outcomes among people, a deeper understanding of how different cancers function and progress …

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Gene Expression Regulation in ALS
Aging, Environment, & Disease

Gene Expression Dysregulation in Familial Amyotrophic Lateral Sclerosis

Researchers have identified a new molecular player involved in the pathology of the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS), and it’s all thanks to the humble fruit fly. A recent study by Mallik et al in the Journal of Cell Biology took advantage of the tractable genetics of the model …

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