Aging, Environment, & DiseaseChromatin Structure

Chromatin Remodelers: A new suspect wanted for questioning regarding their role in the development of cancer

Chromatin remodelers are famous for their ability to mobilize nucleosomes and modify DNA structures. However, mutations in chromatin remodelers are being frequently cited for their implications in cancers and are now almost as notorious as p53 (Shain and Pollack, 2013), with perhaps more sinister activities. This includes mutations amongst members …