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Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Epigenetic drift versus the Epigenetic clock: distinct relationships between DNA methylation and aging

Commentary written by Meaghan Jones and Sarah Goodman Your genome is defined at conception, and aside from rare mutations, it is relatively fixed over your lifetime. Your epigenome, on the other hand, is a balance of responsiveness and heritability. The epigenome can change with specific exposures or experiences, and has …

Aging, Environment, & DiseaseDNA Methylation and HydroxymethylationHistone ModificationsRegulatory RNA

The Role of Epigenetics in Cognitive Ageing

Dr. Karen Mather, Genetics & Genomics Group Leader at the Centre for Healthy Brain Ageing (CHeBA), UNSW Australia As we age, there is a decline in cognitive performance but there is great variability in the rate and degree of cognitive ageing observed across older adults.  The domains of information processing …