Seafood toxins alter DNA methylation
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Sex-specific Alterations in DNA Methylation from Prenatal Exposure to Seafood Toxins

Exposure to toxins in the womb can alter DNA methylation in the offspring [1], [2], persisting after birth [3]. Changes in DNA methylation in umbilical cord white blood cells (UCWBCs) have been linked to increased prevalence of disease, such as asthma [4]. To date, studies have dealt with a single …

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Epigenetics and Allergies
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

New Year, New Hay Fever Season, and New Role for Epigenetics in Allergies

Itching of the eyes and nose, nasal congestion, sneezing, and runny nose are some symptoms of Allergic Rhinitis, better known as hay fever or seasonal allergies, which affects ~30% of people worldwide. In a recent PLOS Genetics publication, scientists from Sweden and the US investigated genome-wide DNA methylation and gene …

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Aging, Environment, & DiseaseDevelopmental Biology & Stem CellsDNA Methylation and HydroxymethylationImprinting and Inheritance

Dad’s Deficient Diet Harms His Offspring: Epigenetics To Blame?

Doctors have long known that a pregnant woman needs adequate levels of folate (also known as vitamin B9) to help prevent serious birth defects. New research in mice now suggests that a father’s level of folate prior to conception also plays a critical role in the baby’s health, through a …

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Epigenetics of exercise
Article SummariesDNA Methylation and Hydroxymethylation

Exercise: No Pain, No Gain (in DNA Methylation)

Through twin studies and the use of laboratory mice, it is becoming increasingly clear that epigenetic patterns are heavily influenced by the environment. These influences can be either harmful or beneficial to our health. For example, long-term smokers often exhibit characteristic changes in the DNA methylation patterns of key genes …

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Epigenetics of Hamster Reproduction
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Fall is in the Air: DNA Methylation Regulates Seasonal Hormonal Changes in Hamsters.

Ah the fall…the leaves are changing color, you can feel a chill in the air, the days are getting shorter, and your libido is decreasing…wait, what?!?  Well, maybe not in humans, but seasonal changes that affect the length of day, or photoperiod, can have a profound effect on reproductive behavior …

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lose_weight
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Want To Lose More Weight With Less Effort? Epigenetics Can Help.

Genetic and lifestyle factors both play important roles in controlling our weight, and epigenetics has recently emerged as a powerful new tool to study the effects of lifestyle on obesity. Epigenetic mechanisms regulate heritable patterns of gene expression without changes in the DNA sequence through numerous processes, including DNA methylation …

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fist bump
Developmental Biology & Stem CellsDNA Methylation and HydroxymethylationImprinting and Inheritance

Yet Another Reason to Thank Dad This Father’s Day! Evidence for Paternally-Inherited Epigenetic Modifications

Maternal health during gestation and prenatal conditions are well documented as having profound effects on health and development of a baby after birth. The mechanisms behind many of these effects are attributed to epigenetic changes that take place in utero. More recently, pre-fertilization maternal health has been also been implicated …

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turmeric
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Digging for Answers: The Potential of Curcumin as an Epigenetic Therapeutic Drug to Treat Cancer

The brilliant golden powder of turmeric is best known as the main spice in curry, but has also been widely used for many years in Eastern traditional medicines as an anti-inflammatory agent.  Turmeric has been used as an alleviator for arthritis, stomach pain, and cancer, among many other health issues. …

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