SNP-SNP here, SNP-SNP there, everywhere a SNP-SNP, old McDonald had a GWAS……
Aging, Environment, & DiseaseChromatin StructureTools & Technology

SNP-SNP here, SNP-SNP there, everywhere a SNP-SNP, old McDonald had a GWAS……

Gerhard A. Coetzee, Wange Lu, Peggy Farnham USC Genome-wide association studies (GWAS) have revealed numerous single-nucleotide polymorphisms (SNPs) where allelic frequencies differ between cases and controls of many complex diseases (NHGRI GWA Catalog). In the last decade 6,696 genetic associations of 598 traits have been reported in 16,770 papers (up …

READ MORE →
Mitochondria Bioenergetics
Aging, Environment, & DiseaseDevelopmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

The Mitochondrial Epigenetics Revolution: A New Avenue for Potential Research

The mitochondria, often referred to as the “power-house” of the cell, provide a platform for energy production through glucose metabolism. As a bi-product of this, they also are the major producer of reactive oxidative species. Mitochondria also play other important physiological roles, such as calcium homeostasis and aid in the …

READ MORE →