A Flash-Frozen View of Condensing Chromatin
Chromatin Structure

A Flash-Frozen View of Condensing Chromatin

For cells to divide, they must first condense their DNA into the X-shape familiar from introductory biology textbooks. While the process of cell division has been studied for over 100 years, how exactly our DNA condenses in three-dimensions within the nucleus remains a mystery. To better understand this condensation process, …

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DNMT3
Chromatin StructureDNA Methylation and Hydroxymethylation

Choosy DNA Methyltransferases Choose CpG-Dense Regions

While changes in DNA methylation have been implicated in a variety of diseases, there is still much to learn about the cellular regulation of DNA methylation patterns across the genome. De novo methyltransferases DNMT3A and B are known to establish DNA methylation. In a recent paper, Baubec et al. investigated …

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