How Jet Lag Impacts Epigenetics
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Up All Night and Asleep All Day: How Jet Lag Impacts Epigenetics

Anyone who has ever dragged themselves off of a red-eye flight, understands the exhaustion of jet lag. Depending on how far you’ve traveled, the effects of jet lag can last from days to weeks, leading to sleepless nights and tired days as your body attempts to reset its circadian clock. …

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Can Epigenetics Fix a Broken Heart? Epigenetic Modifications Enhance the Cardiac Competency of Adult Stem Cells
Aging, Environment, & DiseaseHistone ModificationsTools & Technology

Can Epigenetics Fix a Broken Heart? Epigenetic Modifications Enhance the Cardiac Competency of Adult Stem Cells

          In Mathias Malzieu’s novel “The Boy with the Cuckoo-Clock Heart”, Jack is born with a frozen, dysfunctional heart which, fortunately for him, is soon replaced with a workable heart made from a cuckoo clock. If found in a similar situation, who would not desire such an amazing, albeit strange, miracle? …

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hypertriacylglycerolaemia
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Hypertriacylglycerolaemia: Genetic and epigenetic factors jointly regulate circulating triacylglycerol levels

Apolipoprotein A5 gene (APOA5) is one of the genes implicated in contributing to a  predisposition for hypertriacylglycerolaemia (HTG),  a complex polygenic pathology that is highly influenced by environment. Hypertriacylglycerolaemia is characterized by having high circulating triacylglycerol levels and is a significant risk factor for cardiovascular disease and atherosclerosis. This genetic …

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