Aging, Environment, & DiseaseDNA Methylation and HydroxymethylationHistone Modifications

Mitochondrial epigenetics: Effects beyond the nuclear genome

  From playing a role in heritable changes to somatic mutations, including associations with diet, exercise, and other lifestyle interventions, epigenetics is progressively becoming implicated in a wide variety of activities and diseases. While the role of epigenetics has been predominately thought of in terms of genomic DNA, a clear …

Mitochondria Bioenergetics
Aging, Environment, & DiseaseDevelopmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

The Mitochondrial Epigenetics Revolution: A New Avenue for Potential Research

The mitochondria, often referred to as the “power-house” of the cell, provide a platform for energy production through glucose metabolism. As a bi-product of this, they also are the major producer of reactive oxidative species. Mitochondria also play other important physiological roles, such as calcium homeostasis and aid in the …