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Frog Eyes Might Be Key to Retinal Regeneration

Frog Eyes Might Be the Key to Retinal Regeneration

Often said to be the windows to the soul, our eyes are one of the main ways we perceive the world around us. Vision loss, whether due to aging or injury, can be devastating and often hinders the ability to work, leading to economic stress [1]. Current treatments for vision …

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C. elegans Histone Methyltransferase Targets Regions to Silence

How a C. elegans Histone Methyltransferase Targets Regions to Silence

As an organism grows and develops, its cells are rapidly dividing and committing to different fates. Some, for example, will become immune cells, while others will become skin cells. What decides the different fates of these cells is how their genes are expressed. For example, to become a skin cell, …

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Altering Heterochromatin Disguises Malaria from Host

Hidden in Plain Sight: How Altering Heterochromatin Disguises Malaria from its Host

Like a criminal adopting a disguise to evade detection, malaria parasites inside red blood cells express specific proteins on the blood cell surface to hide from the immune system. When the malaria parasites, Plasmodium falciparum, are eventually detected, they simply switch the identity of the surface protein in a process …

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Low HDAC3 Expression Leads to Endometriosis-Linked Infertility

Low HDAC3 Expression Leads to Endometriosis-Linked Infertility

From fostering the development of new life to literally pushing out a 6 to 10-pound baby, the uterus is a pretty phenomenal organ. Every month it thickens its endometrial cells, the cells that line the inner wall of the uterus, in preparation for implantation of an embryo. But, if implantation …

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How Foreign DNA is Hushed

Cellular Antivirus: How Foreign DNA is Hushed

Like a computer antivirus, our cells are constantly on the lookout for things that do not belong. Our body’s first line of defense, immune cells, circulate through the bloodstream and attack anything they perceive as different, but what happens when something foreign manages to avoid the immune system long enough …

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HDAC Inhibitor Stops HPV in its Tracks

HDAC Inhibitor Stops HPV in its Tracks

It may come as a surprise for a virus to be name-dropped during a stand-up comedy show, but in Ali Wong’s Netflix special “Baby Cobra” she exclaims, “Everybody has HPV, OK? Everybody has it… If you don’t have it yet, you go and get it.”

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Epigenetic Regulators Are Important for Maintaining Bone Homeostasis

Balancing Bones: Epigenetic Regulators Are Important for Maintaining Bone Homeostasis

Walking the dog is not typically considered a dangerous task, but when an unexpected tug on the leash leads to a fall and a broken hip, it certainly becomes one. As we age, the balance between the formation of new bone and the removal of old bone shifts. New bone …

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Histones in Paternal Epigenetic Inheritance

A Role for Histones in Paternal Epigenetic Inheritance

A group of children grew up in the same neighborhoods of Quebec in the late 1960’s, but only some of them would reach their fifth birthday. In one of the first studies of its kind, Fabia and Thuy combed through hospital records to ask what made these children different from …

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