Beneficial Effect of Exercise on DNA Methylation

The Beneficial Effect of Exercise on DNA Methylation

As difficult as it may be to drag ourselves out of bed in the morning to go for a run or fit in a quick trip to the gym after work, regular exercise is essential for a healthy life. Research has shown that regular physical exercise reduces the risk of …

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How Jet Lag Impacts Epigenetics

Up All Night and Asleep All Day: How Jet Lag Impacts Epigenetics

Anyone who has ever dragged themselves off of a red-eye flight, understands the exhaustion of jet lag. Depending on how far you’ve traveled, the effects of jet lag can last from days to weeks, leading to sleepless nights and tired days as your body attempts to reset its circadian clock. …

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Epigenetic Link to Recurrent Miscarriage

An Epigenetic Link to Recurrent Miscarriage

Miscarriage, or natural loss of a pregnancy, is a common reproductive problem and can be upsetting for families trying to have a child. Recurrent miscarriage (RM) – two or more miscarriages – often occur because of problems that arise very early in embryonic development. A common cause of RM is …

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MicroRNAs Take Down Brain Cancer

MicroRNAs Team Up to Take Down Brain Cancer

MicroRNAs are small but powerful molecules in the cell. Containing only around 22 nucleotides, these small RNA molecules are responsible for binding to and silencing messenger RNA sequences before they can be translated into proteins, and thus are incredibly important regulators of gene expression. MicroRNAs (miRs) often regulate the expression …

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Low HDAC3 Expression Leads to Endometriosis-Linked Infertility

Low HDAC3 Expression Leads to Endometriosis-Linked Infertility

From fostering the development of new life to literally pushing out a 6 to 10-pound baby, the uterus is a pretty phenomenal organ. Every month it thickens its endometrial cells, the cells that line the inner wall of the uterus, in preparation for implantation of an embryo. But, if implantation …

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Tau on the Epigenome of Alzheimer’s Brains

Untangling the Role of Tau on the Epigenome of Alzheimer’s Brains

Forgetting where you put your car keys or the address of your aunt’s house is pretty normal, but for people with Alzheimer’s disease, this kind of forgetfulness and memory loss is just the tip of the iceberg. As the neurons in the brains of these patients degenerate, their memory loss …

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How Foreign DNA is Hushed

Cellular Antivirus: How Foreign DNA is Hushed

Like a computer antivirus, our cells are constantly on the lookout for things that do not belong. Our body’s first line of defense, immune cells, circulate through the bloodstream and attack anything they perceive as different, but what happens when something foreign manages to avoid the immune system long enough …

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Implicating Methylation Variability in Depression

Implicating Methylation Variability in Depression

When Scott Kelly touched back down to Earth after nearly a year in space, scientists found that he was no longer strictly identical to his twin brother Mark [1]. While Scott’s DNA sequence was no different from his brother’s, he did have a number of epigenetic changes compared to Mark. …

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