Stem Cell Cultures
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Differing culture conditions can lead to both reversible and irreversible changes in DNA methylation.

Investigation into the mechanisms of pluripotency in stem cells and their potential applications is ongoing.  It is of utmost importance that these cells be propagated stably, both for the consistency of data within the scientific community and then also for potential clinical applications.  How do culture conditions impact methylation and …