Developmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

DNA Methylation and Hydroxymethylation in Stem Cells

Ying Cheng, Nina Xie, Tao Wang Stem cells, including embryonic stem cells (ESCs) and adult stem cells (ASCs), are undifferentiated cells that can differentiate into specialized cells and self-renew through mitosis. These stem cell identities and functions are highly controlled by epigenetic regulation, including DNA methylation, histone modifications and nucleosome …