Transient Imprinting of Genes in the Human Placenta
Developmental Biology & Stem CellsDNA Methylation and Hydroxymethylation

Transient Imprinting of Genes in the Human Placenta

When the fertilization occurs, the maternal and paternal pronuclei have thousands of opposite methylated regions. Most of this germline methylation are resolved during the postfertilization epigenetic reprogramming by active mechanism for the sperm-derived methylated regions and depending on DNA replication for the oocyte-derived ones. There is a subset of regions …

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