HUNTINGTON’S DISEASE
Aging, Environment, & DiseaseHistone Modifications

A Consistent Signature of Histone Deacetylation in Huntington’s Disease?

Huntington’s disease (HD) is a fatal neurodegenerative disorder that affects 5 to 10 people per 100,000 inhabitants. Despite the identification of the primary cause of the disease 20 years ago (an aberrant expansion of trinucleotide CAG repeats in the exon 1 of the huntingtin gene), there is still no effective …

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