Cigarette Smoking, Epigenetics, and DNA Methylation
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Cigarette Smoking and Epigenetics: DNA Methylation Differences Between Ethnic Groups

Cigarette smoking leads to some of the most preventable causes of death and illness in the world. The Centers for Disease Control (CDC) in the United States has reported that there are approximately 440,000 deaths due to smoking each year, and an additional 49,000 deaths due to secondhand smoke.  Roughly …

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Epigenetics and PTSD
Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Connecting Epigenetics and Memory to PTSD

1 in 5.  That is the statistic for Iraq and Afghanistan war veterans that have been diagnosed with Post-Traumatic Stress Disorder (PTSD), according to the Department of Veteran Affairs. PTSD is a severe psychological condition that can develop after witnessing traumatic events, and its symptoms include disturbing flashbacks, anxiety, distress, …

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Patenting Genes
Tools & Technology

Patenting Genes: Human Invention or Product of Nature?

Leading up to the debate on gene patenting, this week marks the 60th anniversary of the discovery of the DNA double helix. On April 25th, 1953 the work of James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin and other colleagues on the structure of DNA was published in Nature. Without …

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Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Hope for the Future: MTHFR as a Novel Biomarker for Infertility

The field of epigenetics plays a key role in multiple developmental diseases and processes. When dealing with infertility issues, DNA methylation should be looked at as a potential factor. Approximately 1% of infertile couples experience Recurrent Spontaneous Abortion (RSA), defined as the miscarriage of two or more pregnancies before 20 …

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Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Here today, gone tomorrow: The Genome-Wide Absence of 5-hmC in Melanomas

Melanoma is an aggressive form of skin cancer that occurs at a higher frequency with increasing age, in addition to environmental contributions, such as exposure to UV light. In fact, it accounts for 75% of all skin cancers and occurs more commonly in women than men. Melanoma tumors were previously …

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The kidneys are responsible for salt reabsorption in the body
Aging, Environment, & DiseaseHistone Modifications

Epigenetic and dietary regulation of salt-sensitive hypertension

Hypertension (also known as high blood pressure) is a disease that is often heritable and can be a direct consequence of dietary factors.  A high intake of dietary salt is one factor that can potentially affect the expression of genes involved in regulating blood pressure, and thus contributes to the …

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