Imaging technique reveals a unique epigenetic state in mammalian genome
DNA Methylation and HydroxymethylationTools & Technology

Imaging technique reveals a unique epigenetic state in mammalian genome

Epigenetic modifications are chemical processes that affect gene activity without altering the DNA sequencing. The two major DNA epigenetic modifications in the mammalian genome are 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), which are often referred to as the “fifth base” and “sixth base,” respectively. 5mC is generated by DNA methyltransferase (DNMTs) …

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