Aging, Environment, & DiseaseDNA Methylation and HydroxymethylationHistone Modifications

Mitochondrial epigenetics: Effects beyond the nuclear genome

  From playing a role in heritable changes to somatic mutations, including associations with diet, exercise, and other lifestyle interventions, epigenetics is progressively becoming implicated in a wide variety of activities and diseases. While the role of epigenetics has been predominately thought of in terms of genomic DNA, a clear …

Aging, Environment, & DiseaseDNA Methylation and Hydroxymethylation

Obesogens: The epigenetic interaction between nature and nurture on risk of obesity

More than 35% of the U.S. population is considered clinically obese (body mass index of > 30), while 68% of the U.S. is considered overweight (body mass index of > 25) 1. Obesity is known to have adverse health effects, impacting the risk and prognosis for a number of diseases, …